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Technology

arcoris nanotechnology: Multimodal Universal Signal Enhancement, MUSE:
unmatched flexibility with uncompromising precision

1. Detection

Standard smFISH or immunostaining protocols

Advantages

Universal

Same chemistry for FISH and IF facilitates combined detection.

Real Multiplex

No need for staining cycles.

High Gain

Good for smFISH on FFPE

Cost effective

No specialised equipment required. 

Fast

1-2 day protocols for 5-plex results

Multimodal

Combine and exchange labels depending on your needs. 

Easy to deploy

Rapid deployment to new or custom assays.

Comparison to alternatives

TSA has to be repeated n-times for n-plex resulting in long protocols and sample degradation.

bDNA approaches require care and specialised equipment due to the very long amplifiers.

smFISH is limited by low signal.

Primary antibodies cannot be freely combined when using secondaries for signal amplification.

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